Find clinical guidelines

Describe a patient presentation or clinical decision point and Anara searches PubMed, ClinicalTrials.gov, and your library for current guidelines, trial data, and systematic review evidence, with every source cited. Use it for the evidence behind a recommendation before a complex case or presentation. It is not a point-of-care dosing reference.

Prompt

A hospitalist physician prepares for a ward round involving a resistant organism in a comorbid patient.

My patient is a 62-year-old female with type 2 diabetes and stage 3 CKD presenting with a urinary tract infection. The urine culture shows Staphylococcus haemolyticus resistant to ampicillin, oxacillin, tetracycline, and penicillin G.

Search PubMed and ClinicalTrials.gov for:
1. Current guideline recommendations for antibiotic selection in resistant S. haemolyticus UTI in a patient with CKD
2. Any RCTs or cohort studies on antibiotic outcomes in this organism and resistance profile
3. Whether any guidelines specifically address dose adjustment for the recommended antibiotic in stage 3 CKD

Cite every guideline or study you reference. Flag any recommendation where the evidence is based on expert consensus rather than trial data.

What to add to your library

• Required: nothing to upload. The prompt carries the clinical question and Anara searches live databases.
• Optional: papers from your library on the condition or organism, searched alongside PubMed and ClinicalTrials.gov.
• Optional: the guideline body to prioritize (NICE, ADA, IDSA, ESC).

What you get

• Current guideline recommendations and the primary trial data behind them.
• Recent studies that qualify or extend the standard guidance.
• A citation with a link for every guideline and study, and an explicit flag where a recommendation rests on expert consensus.

Follow-ups

Compare two guidelines on the same condition.

Compare the NICE and IDSA recommendations for antibiotic treatment of resistant S. haemolyticus urinary tract infections. Where do they agree, where do they diverge, and what evidence does each cite to support its recommendation?

Identify gaps in the evidence for your patient.

Which aspects of the antibiotic guidance for this case rely on evidence drawn from immunocompetent patients or patients with normal renal function, rather than patients with CKD? Name the gaps explicitly and indicate whether any studies have addressed them.

Tips

• Name the organism, resistance profile, and comorbidities. "UTI antibiotic selection" returns general guidance.
• Asking to flag consensus-based recommendations separately turns a summary into an evidence map.
• The index lags days to weeks for very recent publications. For fast-moving guidance, check the cited guideline date and the organization's website.
• Clinical decisions remain yours. The summary informs judgment; it does not replace it.