Study a set of trials

Upload a folder of trial papers and Anara produces a complete study guide covering pharmacology, trial designs, every endpoint with statistics, adverse events, limitations, and clinical implications. Use it before a formulary presentation, evidence review board, or journal club where every number is fair game.

Prompt

A clinical pharmacy faculty member builds a guide from a folder of trials on combination antibiotic therapy.

Prompt

Before proceeding, establish these ground rules: from this point forward, all responses must be based exclusively on the materials in my folder. Do not use external knowledge or supplement with information not present in these documents.

Deeply analyze every PDF in the folder "Triple Antibiotic Therapy Trials." Give me a comprehensive clinical study guide covering:
1. Pharmacologic rationale for triple therapy versus standard of care
2. Key trial designs: phase, patient population, inclusion and exclusion criteria, comparators
3. Primary endpoints: measure, reported result, confidence interval, p-value for each trial
4. Secondary endpoints: all reported, with statistics
5. Adverse event profiles: rates, severity grading, discontinuations due to AE
6. Limitations of the evidence base as reported by the study authors
7. Clinical implications and where the evidence is insufficient or conflicting

Do not miss anything. If I feel you are missing data, I will ask you to go back.

What to add to your library

Required: a folder containing the clinical trial publications you want analyzed.
Optional: the clinical question or formulary decision the guide supports.
Optional: the therapeutic area, so Anara uses the right vocabulary for endpoints and safety reporting.

What you get

A cited guide with a section for each trial and every endpoint reported with its full statistics.
Adverse event data organized by frequency and severity.
Explicit notes wherever the evidence is insufficient or conflicting, rather than smoothed over.

Follow-ups

Find where the trials disagree.

Prompt

Across all trials in the folder, identify every outcome measure where the studies report conflicting results. For each conflict, name the trials, the reported values, and any methodological difference that might explain the discrepancy.

Condense it for a formulary submission.

Prompt

Write a 400-word clinical evidence summary suitable for a formulary submission. Cover the strength of the evidence base, the primary efficacy outcomes, the significant safety signals, and the main limitations. Cite the specific trials for every claim.

Tips

Set the "exclusively from these materials" ground rule first, and push back if a section feels compressed. Without it, general clinical knowledge mixes in and the guide is harder to audit.
Cross-check adverse event rates against each paper's safety tables, and watch for adjusted versus unadjusted statistics.
When new trials publish, add them to the folder and ask Anara to update the relevant sections instead of regenerating.